Laboratory of Experimental Biological Models

  • plans and carries out biological irradiation experiments,
  • manages animal research facility,
  • experiments with simulation models of in vivo radiation-induced pathologies, elaborates and tests new correction methods,
  • studies spontaneous and induced mutagenesis and carcinogenesis in biological models exposed to ionizing radiation,
  • studies cell radiosensitivity mechanisms of normal and cancer cells,
  • studies innovative medicinal substances with radiomodifying properties.

Established in September 2014.



MEDVEDEVA Elena, junior researcher
CHUBUKOVA Tatiana, junior researcher
PILOTOVICH Anastasia, junior researcher
FABUSHEVA Ksenia, junior researcher
NOVITSKAYA Snezhana, junior researcher
DVORNIK Yulia, junior researcher
VASILETS L.P., lab assistant
MOKROUS Tamara, lab assistant
SYUSKINA Elena, lab technician

Bionanoscopy Sector

STARODUBTSEVA Maria, Head of Sector
TSUKANOVA Еlena, junior researcher
SHKLIARAVA Nastassia, junior researcher
CHELNOKOVA Irina, junior researcher

The lab premises house a Vivarium, a special research facility for keeping and breeding laboratory animals. The Vivarium is being managed in compliance with the requirements of the Sanitary Rules and Norms on the Establishment, Equipment and Maintenance of Experimental Biological Clinics (Vivariums). The animal facility staff are highly qualified specialists with many years of experience in lab animal management and animal experimental research.

The quality of laboratory specimen essentially determines the quality of the whole experiment. Under constantly increasing demands for the quality of laboratory animals, our Vivarium managers put their best efforts to provide the highest conformity to the standards of test animals.

In 2019, within the framework of Gratuitous Aid Agreement between Mission Support and Test Services, LLC (USA) and IRB, the lab equipment was essentially reinforced with an X-ray biological irradiation unit X-RAD 320, a self-contained x-ray system designed to deliver a precise radiation dosage to biological samples and small laboratory animals.

The X-RAD 320 unit offers the ability to experiment either with irradiation of the whole animal body or its specific parts and areas. Irradiation of cell cultures and suspensions in experiments in vitro is another advantageous ability of this instrument.

Our biological irradiation unit is equipped with a built-in OptiMAX imaging module used in the variety of radiation therapy research and producing high-resolution optical molecular and x-ray images.

This unit is a perfect use for the variety of research purposes, from modelling ionizing radiation-induced pathologies and studying the mechanisms and effects of ionizing radiation at different organizational levels of biological systems to working out the ways of correction of somatic and cancerous diseases and evaluating remedial effects from different medicinal substances and materials.

Our Bionanoscopy Sector is equipped with state-of-the-art laboratory research units including an AFM BioScope Resolve and an inverted fluorescence microscope Axio Observer 3 offering us an ability of a high-resolution examination of structural, mechanical and other cell properties, live cells in liquid media, nanoparticles etc.


  1. V. P. Gerasimenia, S. V. Zakharov, K. Z. Gumargalieva, T. I. Milevich. Extracts from basidium fungi and their multifunctional medical and biological action (in Russian). Ed. by V. Poliakov. M.: Inbiopharm, 2014. P. 150.
  2. The bioactive properties of aqueous extracts of cultured mushrooms Hericium erinaceus (in Russian). N. I. Timokhina, S. N. Sushko, N. N. Veyalkina [et al.]. Problems of Health and Ecology, 2017. No. 2, Vol. 52. P. 71–74.
  3. Genetically-caused tumor formation in lungs of mice of line Af under influence of radiation and chemical factors, and at aging (in Russian). N. I. Timokhina, E. A. Nadyrov, N. N. Veyalkina, S. N. Sushko [et al.]. J. of Anatomy and Histopathology, Voronezh, Russia. 2018. No. 3. P. 56–60.
  4. V. V. Truhonovets, E. M. Kadukova, N. N. Veyalkina [et al.]. Cultural introduction of medicinal mushroom Ganoderma lucidum (W. Curt.: Fr.) P. Karst and its potential use under radioactive contamination (in Russian). J. of Bel. State University. ECOLOGY, 2019, No. 4. P. 62–70.
  5. Nano- and microscale mechanical properties of erythrocytes in hereditary spherocytosis. M. N. Starodubtseva, I. A. Chelnokova [et al.]. J. of Biomechanics. 2019. Vol. 83. Р. 1–8.
  6. Assessment of population radiation exposure at the edge of the exclusion zone 32 years after the Chernobyl accident: methods and preliminary results. J.-M. Bertho, M. Maître, P. Croüail, W. Naito, N. Shkliarava [et al.]. Radioprotection. 2019. 54(4). P. 247–257.

Contact details:

Phone number: +375 (232) 68 37 72